Anthony Joshua concedes he doesn't know whether Tyson Fury is "coming or going" as he casts doubt over the all-British bout.
There is a huge demand for the two heavyweights to finally square off the ring.
Joshua and Fury can both lay claim to being top of their division following their recent wins.
A fight in 2021 was expected provided the pair see off their respective challengers before that.
Joshua defends his WBA, WBO and IBF titles next weekend against Bulgarian Kubrat Pulev.
After that though it isn't known who he will fight next as he casts doubt over Fury's willingness to take on the fight, despite stating clearly he wants it himself.
He told ESPN : "When I look at Fury, great talent, but I don't know whether he's coming or going.
"I don't know if he's going to fight Wilder, or if he's not going to fight Wilder, if he's going to fight [Agit] Kabayel, or if he's not going to fight Kabayel.
"He announced he was going to fight me, then the deal didn't get signed and we're not fighting."
The arrival of Oleksandr Usyk into the heavyweight picture also adds further complications.
Following his points win over Derek Chisora the Ukrainian is now WBO's mandatory challenger meaning Joshua would have to take the challenge and put Fury on hold or relinquish the belt and pursue the Gypsy King.
The 31-year-old fully expects Usyk to be his next opponent despite admitting he is keen to take on his compatriot.
"Honestly, I'm keen to test myself. I'm keen to compete with him, no problem," he added.
"But whether he's ready, that's a whole other story because of the issues he faces during his career.
"I don't know what will happen in 2021 but if I was to bet all my money on it I would say Usyk because he is with Matchroom.
"[It's a] straightforward fight, and his track record shows when he says he is going to fight someone, he does."
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