Anthony Joshua defends his heavyweight world titles against Andy Ruiz Jr on Saturday night.
The Brit bids to extend his unbeaten record against the Mexican American who stepped in as a replacement for Jarrell Miller after he tested positive for three banned substances.
Joshua will bid to make a splash on his American debut as he eyes up bigger fights in the future.
But there is plenty of action before the two big men climb through the Madison Square Garden ropes with several Brits bidding to win new fans on the other side of the Atlantic.
Here is your guide to the undercard fights in New York…
Callum Smith vs Hassan N'Dam
Smith makes the first defence of his super-middleweight world title against N'Dam in a fight that was only announced last week.
Smith travelled to Jeddah, Saudi Arabia in September to stop Groves in the seventh round of the final of the lucrative World Boxing Super Series, retiring the defending champion and establishing himself as one of the finest super-middleweights in the world.
Cameroon's N'Dam, a former world middleweight champion, will be an awkward opponent Smith will expect to put him away in the latter rounds.
Chris Algieri vs Tommy Coyle
Coyle has enjoyed something of a late-career renaissance, winning his last three fights since losing to the tricky Tyrone Nurse in 2016.
The Hull man is rarely in a boring fight and this one looks set to be no different as Algieri looks for this third win on the spin.
He has wins over the likes of Ruslan Provodnikov but has fallen short at the highest level against Manny Pacquiao, Amir Khan and Errol Spence.
And he may well have too much for the visiting Coyle.
Katie Taylor vs Delfine Persoon
Taylor has long been the most well-known female boxer in the world and she has the chance to create more history tonight.
The former Irish amateur star will bid to become the undisputed lightweight champion when she takes on Persoon.
Taylor currently holds three of the four world titles with Persoon putting her WBC belt on the line in the Big Apple.
Although she has only lost once, expect the Belgian to struggle against Taylor and fold in the middle rounds.
Josh Kelly vs Ray Robinson
Kelly has looked every inch a future world champion and continues his ring education against the experienced Robinson.
Joshua Buatsi vs Marco Antonio Periban
Buatsi is another stand-out from the 2016 Olympic crop and will have little trouble with an aging Periban who has fought just twice in two years.
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